Sucralfate - CISMeF

Preferred Label : Sucralfate;

NCIt definition : A nonabsorbable, aluminum salt of sucrose orasulfate with anti-ulcer, mucosa-protective and potentially anti-mucositis activity. Negatively charged sucralfate binds, through ionic bond formation, to positively charged proteins on mucosal surfaces, thereby creating a protective coating and physical barrier. This agent may also enhance the production of prostaglandin E2 locally, thereby promoting mucus production, increasing mucosal blood flow and stimulating epithelial proliferation and may contribute to the healing of damaged mucosa.;

Alternative definition : NCI-GLOSS: A drug used to treat ulcers. It adheres to proteins at the ulcer site and forms a protective coating over the ulcer. Sucralfate is also used to treat mucositis.;

UNII : XX73205DH5;

InChIKey : IPLJAZDIICJQEL-JTJNLBSYSA-A;

CAS number : 54182-58-0;

Drug name : Carafate;

Chemical formula : C12H30Al8O51S8.H2O.AlH3O3;

Codes from synonyms : CDR0000045234;

Details

Origin ID

C848;

UMLS CUI

C0038633;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing sucralfate (medicinal product) [SNOMED CT concept]
- Sucralfate [ICD-11 Extension code]
- Sucralfate [LOINC component]
- Sucralfate (substance) [SNOMED CT concept]
- sucralfate [ATC Code]
- sucralfate [Substance BNPC]
- sucralfate [SNOMED Notion]
- sucralfate [MeSH concept]
- sucralfate [MeSH Descriptor]
Validated automatic mappings to BTNT
- sucralfate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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