Tiotropium Bromide

Preferred Label : Tiotropium Bromide;

NCIt related terms : TIOTROPIUM BROMIDE ANHYDROUS;

NCIt definition : The bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity. Although it does not display selectivity for specific muscarinic receptors, on topical application, tiotropium bromide acts mainly on M3 muscarinic receptors located on smooth muscle cells and submucosal glands, preventing smooth muscle contraction and mucus secretion, thus producing a bronchodilatory effect.;

UNII : XX112XZP0J;

InChIKey : DQHNAVOVODVIMG-FOGIBKMMSA-M;

CAS number : 136310-93-5;

Chemical formula : C19H22NO4S2.Br;

NCI Metathesaurus CUI : CL449040;

Details

Origin ID

C84608;

UMLS CUI

C1306772;

CISMeF manual mappings
- Tiotropium Bromide [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Tiotropium Bromide [MeSH Descriptor]
- Tiotropium bromide (substance) [SNOMED CT concept]
- tiotropium bromide [ATC Code]
- tiotropium bromide [MeSH concept]
Validated automatic mappings to BTNT
- tiotropium bromide [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Tiotropium [NCIt concept]
is_salt_form_of
- Tiotropium [NCIt concept]

Keyword's position in hierarchy(ies) :

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