Hepatosplenic T-Cell Lymphoma

Preferred Label : Hepatosplenic T-Cell Lymphoma;

NCIt synonyms : Hepatosplenic Gamma/Delta T-Cell Lymphoma;

NCIt related terms : Hepatosplenic gamma-delta cell lymphoma;

NCIt definition : An extranodal, mature T-cell non-Hodgkin lymphoma that originates from cytotoxic T-cells, usually of gamma/delta T-cell type. It is characterized by the presence of medium-size neoplastic lymphocytes infiltrating the hepatic sinusoids. A similar infiltrating pattern is also present in the spleen and bone marrow that are usually involved at the time of the diagnosis.;

Neoplastic status : Malignant;

ICD-O code : 9716/3;

Codes from synonyms : C86.1;

Details

Origin ID

C8459;

UMLS CUI

C1333984;

Currated CISMeF NLP mapping
- Hepatosplenic T-cell lymphoma [ICD-11 Subcategory]
- Hepatosplenic T-cell lymphoma [MedDRA Preferred Term]
- Hepatosplenic T-cell lymphoma [ORDO Disease]
- Hepatosplenic T-cell lymphoma (disorder) [SNOMED CT concept]
- hepatosplenic T cell lymphoma [Disease (Nov.)]
Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- CD56-Positive Neoplastic Cells Present [NCIt concept]
- Leukocytosis [NCIt concept]
- Thrombocytopenia [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Hepatosplenic T-cell lymphoma [ORDO Disease]
- Hepatosplenic T-cell lymphoma [ICD-10 Sub-category]
- Hepatosplenic T-cell lymphoma [ICD-11 Subcategory]
- Hepatosplenic T-cell lymphoma [MedDRA Preferred Term]
- Hepatosplenic T-cell lymphoma (disorder) [SNOMED CT concept]
- Hepatosplenic gamma-delta T-cell lymphoma [MedDRA LLT]
- hepatosplenic T cell lymphoma [Disease (Nov.)]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Elixhauser Lymphoma Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- CD4-Positive Neoplastic Cells Present [NCIt concept]
- CD8-Positive Neoplastic Cells Present [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelium [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Medium-Sized T-Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Bone Marrow Involvement [NCIt concept]
- Hepatomegaly [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Sinusoidal Infiltration [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_molecular_abnormality
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Hepatobiliary Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
- Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Hepatitis C Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 8 [NCIt concept]
- i(7q) [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
disease_may_have_normal_cell_origin
- Immature Peripheral Alpha/Beta Cell of Cytotoxic Type [NCIt concept]
- Immature Peripheral Gamma/Delta Cell of Cytotoxic Type [NCIt concept]

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