NCIt related terms : U-9889; 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose; Zanosar; U 9889;
NCIt definition : A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces
achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and
inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up
by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike
other nitrosoureas, streptozocin causes little myelosuppression. (NCI04);
Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating
agents.;
UNII : 5W494URQ81;
InChIKey : AGRCPNMCOXLKFO-BDVNFPICSA-N;
CAS number : 18883-66-4;
Drug name : Zanosar;
Molecule name : U-9889;
Chemical formula : C8H15N3O7;
NSC code : 85998;
ChEBI ID : CHEBI:9288;
Codes from synonyms : NSC0085998; 00238; CDR0000045561; 472;