" /> Streptozocin - CISMeF





Preferred Label : Streptozocin;

NCIt synonyms : Streptozotocin; 2-deoxy-2-[[(methylnitrosamino)-carbonyl]amino]-D-glucopyranose; STZ;

NCIt related terms : U-9889; 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose; Zanosar; U 9889;

NCIt definition : A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called alkylating agents.;

UNII : 5W494URQ81;

InChIKey : AGRCPNMCOXLKFO-BDVNFPICSA-N;

CAS number : 18883-66-4;

Drug name : Zanosar;

Molecule name : U-9889;

Chemical formula : C8H15N3O7;

NSC code : 85998;

ChEBI ID : CHEBI:9288;

Codes from synonyms : NSC0085998; 00238; CDR0000045561; 472;

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30/05/2025


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