NCIt synonyms : AF10; DKFZp686E10210; MGC75086; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated
To, 10 wt Allele; Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax (Drosophila) Homolog); Translocated
To, 10 Gene; MLLT10 Histone Lysine Methyltransferase DOT1L Cofactor wt Allele; Myeloid/Lymphoid or Mixed-Lineage Leukemia; Translocated To, 10 Gene; AF-10;
NCIt definition : Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately
209 kb in length. This allele, which encodes protein AF-10, may play a role in the
regulation of transcription. Acute leukemias are associated with a translocation t(10;11)(p12;q23)
involving this gene and the MLL gene. Diffuse histiocytic lymphomas are associated
with a translocation, t(10;11)(p13;q14), involving this gene and the PICALM gene.;