TARBP2 wt Allele

Preferred Label : TARBP2 wt Allele;

NCIt synonyms : TRBP1; TAR (HIV-1) RNA Binding Protein 2 wt Allele; TRBP2; LOQS; TRBP;

NCIt definition : Human TARBP2 wild-type allele is located within 12q12-q13 and is approximately 6 kb in length. This allele, which encodes RISC-loading complex subunit TARBP2 protein, is involved in the modulation of RNA-mediated gene silencing and HIV gene expression. Mutation of the gene may be associated with endometrial, gastric, and colorectal cancers. Loss of the gene may be associated with defective processing of miRNA.;

GenBank Accession Number : NM_134324;

Details

Origin ID

C84408;

UMLS CUI

C2827435;

OMIM relation
- Tar rna-binding protein 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q12-q13 [NCIt concept]
gene_plays_role_in_process
- RNA Interference [NCIt concept]
- Translation Process [NCIt concept]
- Translational Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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