Preferred Label : Prorenoate;
NCIt synonyms : 6,7-Dihydro-17-Hydroxy-3-Oxo-3'H-Cyclopropa(6,7)-17Alpha-Pregna-4,6-Diene-21-Carboxylate; 3'H-Cyclopropa(6,7)Pregna-4,6-Diene-21-Carboxylic Acid, 6,7-Dihydro-17-Hydroxy-3-Oxo-,
(6Alpha,7Alpha,17Alpha)-;
NCIt definition : A steroidal aldosterone antagonist with potassium-sparing diuretic activity. Prorenoate
antagonizes the activity of aldosterone at the mineralocorticoid receptor in the nephron
and thereby prevents sodium reabsorption. This interferes with the sodium/potassium
exchanger and causes sodium and water excretion while reducing potassium excretion.;
UNII : WET36J3301;
InChIKey : OHZWNMVYJJTNKU-VAFIVCJBSA-N;
CAS number : 49848-01-3;
Chemical formula : C23H32O4;
Origin ID : C84117;
UMLS CUI : C3665432;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_salt_form
- is_free_acid_or_base_form_of
