Spiramycin - CISMeF

Preferred Label : Spiramycin;

NCIt synonyms : Provamycin; Antibiotic 799; (4R,5S,6R,7R,9R,10R,11E,13E,16R)-10-{[(2R,5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-9,16-dimethyl-5-methoxy-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-alpha-D-glucopyranoside;

NCIt definition : A macrolide originally discovered as product of Streptomyces ambofaciens, with antibacterial and antiparasitic activities. Although the specific mechanism of action has not been characterized, spiramycin likely inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome. This agent also prevents placental transmission of toxoplasmosis presumably through a different mechanism, which has not yet been characterized.;

UNII : 71ODY0V87H;

CAS number : 8025-81-8;

Drug name : Rovamycine; Rovamycin;

Molecule name : RP 5337;

NSC code : 55926;

Details

Origin ID

C839;

UMLS CUI

C0037962;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing spiramycin (medicinal product) [SNOMED CT concept]
- Spiramycin [ICD-11 Extension code]
- Spiramycin [LOINC component]
- Spiramycin (substance) [SNOMED CT concept]
- demycarosylturimycin H [MeSH Supplementary Concept]
- spiramycin [ATC Code]
- spiramycin [Substance BNPC]
- spiramycin [MeSH concept]
- spiramycin [SNOMED Notion]
- spiramycin [MeSH Descriptor]
Validated automatic mappings to BTNT
- spiramycin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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