Idrapril - CISMeF

Preferred Label : Idrapril;

NCIt definition : A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Idrapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 176P5C4QU8;

InChIKey : QKIVRALZQSUWHH-SFYZADRCSA-N;

CAS number : 127420-24-0;

Chemical formula : C11H18N2O5;

Details

Origin ID

C83780;

UMLS CUI

C0172867;

Currated CISMeF NLP mapping
- idrapril [MeSH concept]
- idrapril [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- idrapril [MeSH Supplementary Concept]
- idrapril [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients