Filibuvir - CISMeF

Preferred Label : Filibuvir;

NCIt synonyms : 2H-Pyran-2-One, 6-Cyclopentyl-6-(2-(2,6-Diethyl-4-Pyridinyl)Ethyl)-3-((5,7-Dimethyl(1,2,4)Triazolo(1,5-A)Pyrimidin-2-yl)Methyl)-5,6-Dihydro-4-Hydroxy-, (6R)-; (6R)-6-Cyclopentyl-6-(2-(2,6-Diethylpyridin-4-yl)Ethyl)-3-((5,7-Dimethyl(1,2,4)Triazolo(1,5- A)Pyrimidin-2-yl)Methyl)-4-Hydroxy-5,6-Dihydro-2H-Pyran-2-One;

NCIt definition : A non-nucleoside polymerase inhibitor of the hepatitis C virus NS5B RNA-dependent RNA polymerase. Filibuvir binds to the non-catalytic Thumb 2 site on viral polymerase and causes a decrease in viral RNA synthesis.;

UNII : 198J479Y2L;

InChIKey : SLVAPEZTBDBAPI-GDLZYMKVSA-N;

CAS number : 877130-28-4;

Molecule name : PF-00868554;

Chemical formula : C29H37N5O3;

Details

Origin ID

C83717;

UMLS CUI

C2827156;

Automatic exact mappings (from CISMeF team)
- filibuvir [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- filibuvir [MeSH concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- filibuvir [MeSH concept]
- filibuvir [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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