Bucillamine - CISMeF

Preferred Label : Bucillamine;

NCIt synonyms : N-(2-Mercapto-2-methylpropionyl)-L-cysteine;

NCIt definition : An orally bioavailable derivative of the endogenous amino acid cysteine with two donatable thiol groups, with potential antioxidant and anti-inflammatory activities. Upon oral administration, bucillamine enters cells rapidly via the same pathway as cysteine and replenishes the thiol group in glutathione (GSH), thereby increasing intracellular GSH levels and GSH activity. GSH is an antioxidant and plays an important protective role in oxidative stress and injury. Bucillamine may have additional anti-inflammatory effects, though the mechanisms of action have yet to be fully elucidated.;

UNII : R80LRA5WTF;

InChIKey : VUAFHZCUKUDDBC-BYPYZUCNSA-N;

CAS number : 65002-17-7;

Chemical formula : C7H13NO3S2;

Details

Origin ID

C83561;

UMLS CUI

C0073917;

Automatic exact mappings (from CISMeF team)
- Bucillamine [ICD-11 Extension code]
Currated CISMeF NLP mapping
- bucillamine [MeSH concept]
- bucillamine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bucillamine [ATC Code]
- bucillamine [MeSH concept]
- bucillamine [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- bucillamine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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