Recombinant Insulin-Like Growth Factor

Preferred Label : Recombinant Insulin-Like Growth Factor;

NCIt synonyms : Somatomedin; Rh Insulin Like Growth Factor; Rh IGF; Therapeutic Insulin-Like Growth Factor;

NCIt definition : A recombinant human antiapoptotic growth factor. Recombinant insulin-like growth factor (IGF) binds to and activates the insulin and IGF receptors; activation of these receptors initiates intracellular phosphorylation events and the activation of several signaling pathways, thereby promoting cellular proliferation and inhibiting apoptosis. High levels of circulating endogenous insulin-like growth factor may indicate a poor prognosis in some cancers. (NCI04);

NCI Metathesaurus CUI : CL938228;

Details

Origin ID

C835;

UMLS CUI

C1522567;

Automatic exact mappings (from CISMeF team)
- Insulin-like growth factor II [OMIM gene]
- Insulin-like growth factor-II [LOINC component]
- Somatomedin A (substance) [SNOMED CT concept]
- insulin like growth factor 2 [ORDO Gene]
- insulin like growth factor 2 [HGNC gene]
- insulin-like growth factor i [MeSH Descriptor]
- insulin-like growth factor ii [MeSH Descriptor]
- somatomedin a [SNOMED Notion]
- somatomedin c [SNOMED Notion]
Currated CISMeF NLP mapping
- Insulin-Like growth factor [OBSOLETE LOINC component]
- Insulin-like growth factor [LOINC component]
- Somatomedin (substance) [SNOMED CT concept]
- Somatomedins [LOINC component]
- somatomedin, nos [SNOMED Notion]
- somatomedins [MeSH Descriptor]
- somatomedins [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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