Amifampridine - CISMeF

Preferred Label : Amifampridine;

NCIt synonyms : Pyridine, 3,4-Diamino-; 3,4-Diaminopyridine; 3,4-Pyridinediamine; 4,5-Diaminopyridine; 3,4-DAP; 3 4-Diaminopyridine;

NCIt definition : An organic compound derived from pyridine with potassium channel inhibition activity. Amifampridine inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract.;

UNII : RU4S6E2G0J;

InChIKey : OYTKINVCDFNREN-UHFFFAOYSA-N;

CAS number : 54-96-6;

Drug name : Firdapse;

Molecule name : SC10;

Chemical formula : C5H7N3;

NSC code : 521760;

Details

Origin ID

C82687;

UMLS CUI

C0046948;

See also inter- (CISMeF)
- Product containing 3,4-diaminopyridine (medicinal product) [SNOMED CT concept]
- Product containing amifampridine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 3,4-diaminopyridine [Substance BNPC]
- Amifampridine [MeSH concept]
- Amifampridine [MeSH Descriptor]
- Amifampridine (substance) [SNOMED CT concept]
- Amifampridine (substance) [SNOMED CT concept]
- Product containing 3,4-diaminopyridine (medicinal product) [SNOMED CT concept]
- Product containing amifampridine (medicinal product) [SNOMED CT concept]
- amifampridine [ATC Code]
Validated automatic mappings to BTNT
- amifampridine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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