" /> Aurora B Serine/Threonine Kinase Inhibitor TAK-901 - CISMeF





Preferred Label : Aurora B Serine/Threonine Kinase Inhibitor TAK-901;

NCIt synonyms : Aurora B Serine Threonine Kinase Inhibitor TAK-901;

NCIt related terms : TAK-901;

NCIt definition : A small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis. This serine/threonine kinase may be amplified and overexpressed by a variety of cancer cell types.;

UNII : DM9UIR23R7;

CAS number : 934541-31-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 934541-31-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : TAK-901;

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Keyword's position in hierarchy(ies) : arborescence

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14/05/2024


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