Aurora B Serine/Threonine Kinase Inhibitor TAK-901

Preferred Label : Aurora B Serine/Threonine Kinase Inhibitor TAK-901;

NCIt synonyms : Aurora B Serine Threonine Kinase Inhibitor TAK-901;

NCIt related terms : TAK-901;

NCIt definition : A small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis. This serine/threonine kinase may be amplified and overexpressed by a variety of cancer cell types.;

UNII : DM9UIR23R7;

CAS number : 934541-31-8;

Molecule name : TAK-901;

Details

Origin ID

C82674;

UMLS CUI

C2826371;

Currated CISMeF NLP mapping
- TAK-901 [MeSH Supplementary Concept]
- TAK-901 [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TAK-901 [MeSH concept]
- TAK-901 [MeSH Supplementary Concept]
chemical_or_drug_affects_gene_product
- Aurora Kinase A [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Aurora Kinase B [NCIt concept]

Keyword's position in hierarchy(ies) :

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