Preferred Label : Beta-Glucan MM-10-001;
NCIt definition : A powder formulation containing a triple helix beta-glucan, isolated from the cell
walls of the shiitake mushroom (Lentinula edodes), with potential immunostimulating
activity. The beta-glucan in beta-glucan MM-10-001 binds to a lectin site within the
complement receptor 3 (CR3 or iC3b receptor) on leukocytes, priming the receptor to
trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to iC3b-opsonized
tumor cells. iC3b is the proteolyticly inactive product of the complement cleavage
fragment C3b.;
Molecule name : MM-10-001;
NCI Metathesaurus CUI : CL388490;
Origin ID : C82657;
UMLS CUI : C2826357;
Semantic type(s)
- concept_is_in_subset
