" /> Afamelanotide - CISMeF





Preferred Label : Afamelanotide;

NCIt synonyms : Melanotan I; Msh, 4-nle-7-phe-alpha-; N-Acetyl-L-serinyl-L-tyrosyl-L-seryl-(2S)-2-aminohexanoyl-L-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanylglycyl-L-lysyl-L-prolyl-L-valinamide;

NCIt definition : A synthetic peptide analogue of the naturally occurring alpha-melanocyte stimulating hormone (a-MSH) with potential photoprotective activity. Mimicking the action of a-MSH, afamelanotide stimulates melanocytes to increase the production and release of melanin. Increased melanocyte melanin may protect against ultraviolet radiation (UVR)-initiated cellular DNA damage, oxidation of membrane proteins, and alterations in intracellular signaling processes in epidermal cells. Endogenously, a-MSH is released by skin cells in response to UVR exposure, stimulating melanocytes to produce and release melanin.;

UNII : QW68W3J66U;

InChIKey : UAHFGYDRQSXQEB-LEBBXHLNSA-N;

CAS number : 75921-69-6;

Molecule name : CUV1647;

Chemical formula : C78H111N21O19;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
22/05/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.