Adult Anaplastic Astrocytoma

Preferred Label : Adult Anaplastic Astrocytoma;

NCIt synonyms : Adult Grade III Astrocytoma; Anaplastic Astrocytoma of Adult; Adult Undifferentiated Astrocytoma; Undifferentiated Astrocytoma of Adult; Grade III Adult Astrocytic Neoplasm; Anaplastic Astrocytoma of the Adult; Undifferentiated Astrocytoma of the Adult; Grade III Adult Astrocytic Tumor; Grade III Adult Astrocytoma; Grade 3 Adult Astrocytic Tumor; Grade 3 Adult Astrocytic Neoplasm; Grade 3 Adult Astrocytoma; Adult Grade 3 Astrocytoma;

NCIt related terms : Anaplastic Astrocytoma;

NCIt definition : An astrocytoma occurring in adults that is characterized by the presence of high mitotic activity, cytologic atypia, and architectural distortion.;

Neoplastic status : Malignant;

Details

Origin ID

C8257;

UMLS CUI

C0280483;

Automatic exact mappings (from CISMeF team)
- Anaplastic astrocytoma [MedDRA Preferred Term]
- Anaplastic astrocytoma [ORDO Disease]
- Astrocytoma, anaplastic [ICD-O code]
- Astrocytoma, anaplastic [ICD-11 Extension code]
- Astrocytoma, anaplastic (morphologic abnormality) [SNOMED CT concept]
- anaplastic astrocytoma [DO Concept]
- astrocytoma [MeSH Descriptor]
- astrocytoma, anaplastic [SNOMED Notion]
Disease may have findings
- Headache [NCIt concept]
- Motor Manifestations [NCIt concept]
- Seizure [NCIt concept]
- Sensory Manifestations [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Central Nervous System [NCIt concept]
- Nervous System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
Validated automatic mappings to NTBT
- anaplastic astrocytoma [MeSH concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Grade 4 Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Necrotic Change [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Astrocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- Adulthood Lesion [NCIt concept]
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Central Nervous System [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 6 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Deletion [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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