Preferred Label : Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7;
NCIt synonyms : Stage IV Larynx Epidermoid Carcinoma; Stage IV Laryngeal Epidermoid Carcinoma; Stage IV Epidermoid Carcinoma of Larynx; Stage IV Laryngeal Squamous Cell Carcinoma; Stage IV Epidermoid Carcinoma of the Larynx; Stage IV Squamous Cell Carcinoma of Larynx; Stage IV Squamous Cell Carcinoma of the Larynx; Stage IV Larynx Squamous Cell Carcinoma;
NCIt related terms : Stage IV Laryngeal Throat Squamous Cell Cancer;
NCIt definition : Stage IV includes: IVA: (T4a, N0, M0); (T4a, N1, M0); (T1, N2, M0); (T2, N2, M0);
(T3, N2, M0); (T4a, N2, M0); IVB: (T4b, Any N, M0); (Any T, N3, M0); IVC: (Any T,
Any N, M1). T4a: Supraglottis: Moderately advanced local disease. Tumor invades through
the thyroid cartilage and/or invades tissues beyond the larynx (e.g., trachea, soft
tissues of neck including deep extrinsic muscle of the tongue, strap muscles, thyroid,
or esophagus). Glottis: Moderately advanced local disease. Tumor invades through the
outer cortex of the thyroid cartilage and/or invades tissues beyond the larynx (e.g.,
trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap
muscles, thyroid, or esophagus). Subglottis: Moderately advanced local disease. Tumor
invades cricoid or thyroid cartilage and/or invades tissues beyond the larynx (e.g.,
trachea, soft tissues of neck including deep extrinsic muscles of the tongue, strap
muscles, thyroid, or esophagus). T4b: Supraglottis, Glottis, and Subglottis: Very
advanced local disease. Tumor invades prevertebral space, encases carotid artery,
or invades mediastinal structures. N0: No regional lymph node metastasis. N1: Metastasis
in a single ipsilateral lymph node, 3cm or less in greatest dimension. N2: Metastasis
in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest
dimension, or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest
dimension, or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest
dimension. N3: Metastasis in a lymph node, more than 6 cm in greatest dimension. M0:
No distant metastasis. M1: Distant metastasis. (AJCC 7th ed.);
Neoplastic status : Malignant;
Origin ID : C8243;
UMLS CUI : C4721434;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
- disease_mapped_to_gene
- disease_may_have_cytogenetic_abnormality
- disease_may_have_molecular_abnormality
