Preferred Label : Actinium Ac 225 Lintuzumab;
NCIt synonyms : Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195; 225Ac-HuM195; Actinium (225Ac) Lintuzumab Satetraxetan;
NCIt related terms : LINTUZUMAB SATETRAXETAN AC-225;
NCIt definition : A radioimmunoconjugate consisting of the humanized monoclonal antibody lintuzumab
conjugated to the alpha-emitting radioisotope actinium Ac 225 with potential antineoplastic
activity. The monoclonal antibody moiety of actinium Ac 225 lintuzumab specifically
binds to the cell surface antigen CD33 antigen, delivering a cytotoxic dose of alpha
radiation to cells expressing CD33. CD33 is a cell surface antigen expressed on normal
non-pluripotent hematopoietic stem cells and overexpressed on myeloid leukemia cells.;
UNII : V860J30J9N;
CAS number : 2209911-94-2;
Drug name : Actimab-A;
Molecule name : SGN-33 AC-225;
NCI Metathesaurus CUI : CL408677;
Codes from synonyms : 10;
Origin ID : C82414;
UMLS CUI : C2826161;
Semantic type(s)
- concept_is_in_subset
