Actinium Ac 225 Lintuzumab

Preferred Label : Actinium Ac 225 Lintuzumab;

NCIt synonyms : Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195; 225Ac-HuM195; Actinium (225Ac) Lintuzumab Satetraxetan;

NCIt related terms : LINTUZUMAB SATETRAXETAN AC-225;

NCIt definition : A radioimmunoconjugate consisting of the humanized monoclonal antibody lintuzumab conjugated to the alpha-emitting radioisotope actinium Ac 225 with potential antineoplastic activity. The monoclonal antibody moiety of actinium Ac 225 lintuzumab specifically binds to the cell surface antigen CD33 antigen, delivering a cytotoxic dose of alpha radiation to cells expressing CD33. CD33 is a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells and overexpressed on myeloid leukemia cells.;

UNII : V860J30J9N;

CAS number : 2209911-94-2;

Drug name : Actimab-A;

Molecule name : SGN-33 AC-225;

NCI Metathesaurus CUI : CL408677;

Codes from synonyms : 10;

Details

Origin ID

C82414;

UMLS CUI

C2826161;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

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