Sizofiran - CISMeF

Preferred Label : Sizofiran;

NCIt synonyms : Schizophyllane; Poly(3-(O-beta-D-glucopyranosyl-(1-3)-O-(beta-D-glucopyranosyl-(1-6))-O-beta-D-glucopyranosyl-(1-3)-O-beta-D-glucopyranosyl)-1);

NCIt definition : A soluble beta-D-glucan produced by the Basidiomycetes fungus, Schizophyllum commune Fries, with potential immunomodulating and antitumor activities. Although sizofiran's exact mechanism of action has yet to be fully elucidated, this agent appears to stimulate the immune system by increasing cytokine production, activating macrophages and enhancing the activity of polymorphonuclear leukocytes (PML) and natural killer (NK) cells.;

UNII : 7F763NNC9X;

CAS number : 9050-67-3;

Drug name : Sonifilan; Sixofilan; MC-Glucan; Schizophyllan;

Chemical formula : (C24H38O19)n;

ChEBI ID : CHEBI:50653;

Details

Origin ID

C824;

UMLS CUI

C0036359;

Automatic exact mappings (from CISMeF team)
- Schizophyllan [MeSH concept]
Currated CISMeF NLP mapping
- sizofiran [MeSH Descriptor]
- sizofiran [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- sizofiran [MeSH Descriptor]
- sizofiran [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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