Preferred Label : Innate Immunostimulator rBBX-01;
NCIt definition : A recombinant 19 kDa protein derived from the Apicomplexa protozoan Eimeria with potential
immunostimulating and antitumor activities. Upon administration, innate immunostimulator
rBBX-01 activates dendritic cells (DCs), stimulates the Toll-like receptor 11 (TLR-11)-mediated
release of interleukin-12 (Il-12) from DCs, and induces a T-helper 1 (Th1) type immune
response, which may induce an immune response against tumor cells. Infection with
Eimeria, a coccidian commonly infecting the intestine, may be negatively correlated
with tumorigenesis.;
Molecule name : rBBX-01;
NCI Metathesaurus CUI : CL408641;
Origin ID : C82362;
UMLS CUI : C2826122;
Semantic type(s)
- concept_is_in_subset
