Preferred Label : M87o-Transduced CD34 Peripheral Blood Stem Cells;
NCIt synonyms : M87o-Transduced CD34 PBSC; Therapeutic Gamma-Retroviral Vector M87o-Transduced CD34 Peripheral Blood Stem Cells; M87o-Transduced CD34 Plus Peripheral Blood Stem Cells;
NCIt definition : Peripheral blood stem cells (PBSCs) transduced with the retroviral vector M87o encoding
for the HIV-1-entry inhibitor peptide membrane-anchored antiviral peptide C46 (maC46).
Expression of C46 by M87o-transduced CD34 peripheral blood stem cells may prevent
the fusion of viral and cellular membranes, thereby inhibiting HIV-1 entry. C46 is
a membrane-anchored peptide encoding amino acids 628 to 673 of the HIV-1 entry inhibitory
transmembrane glycoprotein gp41.;
NCI Metathesaurus CUI : CL408632;
Origin ID : C82351;
UMLS CUI : C2826113;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
