NCIt definition : An orally available benzimidazole riboside compound with activity against cytomegalovirus
(CMV). Maribavir is a selective ATP competitor of viral UL97 kinase, which is involved
in viral nuclear maturation events, such as viral DNA assembly and movement of viral
capsids from the nucleus of infected cells. Maribavir has activity against strains
of CMV that are resistant to standard anti-CMV agents.;
Alternative definition : NCI-GLOSS: A substance that blocks the ability of viruses to make new viruses and
infect cells. It is being studied in the prevention of cytomegalovirus infection in
cancer patients who have had a donor stem cell transplant. It is a type of antiviral
agent.;