" /> Zofenopril Calcium - CISMeF





Preferred Label : Zofenopril Calcium;

NCIt definition : The calcium salt of zofenopril, a sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, zofenopril is hydrolyzed in vivo into its active form zofenoprilat. Zofenoprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Zofenoprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.;

UNII : 88ZQ329PU2;

InChIKey : NSYUKKYYVFVMST-LETVYOFWSA-L;

CAS number : 81938-43-4;

Chemical formula : 2C22H22NO4S2.Ca;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
02/11/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.