Mixed Phenotype Acute Leukemia, T/Myeloid

Preferred Label : Mixed Phenotype Acute Leukemia, T/Myeloid;

NCIt synonyms : Mixed Phenotype Acute Leukemia, T/Myeloid, NOS; Mixed Phenotype Acute Leukemia T Myeloid Not Otherwise Specified; MPAL, T/Myeloid, NOS; Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified;

NCIt definition : A rare mixed phenotype acute leukemia in which the blasts express T-lymphoid and myeloid lineage markers but are negative for KMT2A rearrangement and t(9;22)(q34;q11.2) translocation. The prognosis is usually unfavorable.;

Neoplastic status : Malignant;

ICD-O code : 9809/3;

Details

Origin ID

C82213;

UMLS CUI

C2826055;

Currated CISMeF NLP mapping
- Mixed phenotype acute leukemia with myeloid and T-cell lymphoid phenotypes (morphologic abnormality) [SNOMED CT concept]
Disease may have findings
- Granulocytopenia [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Mixed phenotype acute leukemia with myeloid and T-cell lymphoid phenotypes (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_cytogenetic_abnormality
- t(9;22)(q34.1;q11.2) [NCIt concept]
- t(v;11q23.3) [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Blasts Expressing B-Lymphoid and T-Lymphoid Markers Present [NCIt concept]
- Blasts Expressing B-Lymphoid, T-Lymphoid, and Myeloid Markers Present [NCIt concept]
- Blasts Expressing CD56 and Immature T-Cell Markers Present [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Blast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Blasts Expressing T-Lymphoid and Myeloid Markers Present [NCIt concept]
- Blasts of Mixed Phenotype Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]

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