Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor

Preferred Label : Recombinant Human Albumin-Human Granulocyte Colony-Stimulating Factor;

NCIt synonyms : Recombinant Human Albumin-Human GCSF;

NCIt definition : A long-acting recombinant fusion protein incorporating human serum albumin (HSA)-derived and human granulocyte colony stimulating factor (G-CSF)-derived moieties with potential granulopoietic activity. G-CSF, a naturally occurring cytokine, stimulates the production of granulocytes and stem cells in the bone marrow and their release into the blood; it also stimulates the differentiation, function, and survival of neutrophil precursors and mature neutrophils. Albumin fusion may promote an increased serum half-life and bioavailability of the G-CSF moiety of this fusion protein.;

Drug name : Neugranin;

Molecule name : GW003;

NCI Metathesaurus CUI : CL407460;

Details

Origin ID

C81936;

UMLS CUI

C2825833;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Hematopoietic Stem Cell [NCIt concept]
chemical_or_drug_affects_gene_product
- GM-CSF Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Positive Regulation of Cell Differentiation [NCIt concept]
- Receptor Activation Process [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients