Laryngeal Verrucous Carcinoma

Preferred Label : Laryngeal Verrucous Carcinoma;

NCIt synonyms : Verrucous Carcinoma of the Larynx; Verrucous Carcinoma of Larynx; Larynx Verrucous Carcinoma;

NCIt related terms : Laryngeal Throat Verrucous Cancer;

NCIt definition : A well differentiated, non-metastasizing squamous cell carcinoma arising from the larynx. It is an exophytic, warty, and slow growing tumor affecting predominantly older men. It is associated with tobacco smoking. Symptoms include hoarseness, airway obstruction, weight loss, dysphagia, and throat pain. If left untreated, it may cause extensive local destruction.;

Neoplastic status : Malignant;

Details

Origin ID

C8188;

UMLS CUI

C0280328;

Automatic exact mappings (from CISMeF team)
- Primary verrucous carcinoma of larynx (disorder) [SNOMED CT concept]
- Verrucous carcinoma of larynx [ICD-11 More detail]
- larynx verrucous carcinoma [DO Concept]
Currated CISMeF NLP mapping
- Laryngeal verrucous carcinoma [MedDRA LLT]
DO Cross reference
- larynx verrucous carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Airway Obstruction [NCIt concept]
- Dysphagia [NCIt concept]
- Hoarseness [NCIt concept]
- Pain [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
- Intrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Larynx [NCIt concept]
- Neck [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Laryngeal verrucous carcinoma [MedDRA LLT]
- larynx verrucous carcinoma [DO Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Pseudopapillary Pattern [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Acanthosis [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Endophytic Tumor Growth [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Exophytic Papillary Lesion [NCIt concept]
- Hyperkeratosis [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mild Cytologic Atypia [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
- Pushing Tumor Margin [NCIt concept]
- Well Differentiated Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Laryngeal Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Larynx [NCIt concept]
- Neck [NCIt concept]
- Throat [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 11q13 [NCIt concept]
- Gain of Chromosome 14 [NCIt concept]
- Gain of Chromosome 17q [NCIt concept]
- Gain of Chromosome 1q [NCIt concept]
- Gain of Chromosome 3q [NCIt concept]
- Gain of Chromosome 5p [NCIt concept]
- Gain of Chromosome 7p [NCIt concept]
- Gain of Chromosome 7q [NCIt concept]
- Gain of Chromosome 8q [NCIt concept]
- Gain of Chromosome 9q [NCIt concept]
- Loss of Chromosome 18q [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
disease_may_have_molecular_abnormality
- EGFR Protein Overexpression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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