Tonsillar Squamous Cell Carcinoma

Preferred Label : Tonsillar Squamous Cell Carcinoma;

NCIt synonyms : Squamous Cell Carcinoma of Tonsil; SCC of the Tonsil; SCC of Tonsil; Tonsil Squamous Cell Carcinoma; Tonsil SCC; Squamous Cell Carcinoma of the Tonsil; Tonsillar SCC;

NCIt definition : A squamous cell carcinoma that arises from the mucosal lining of the tonsil and tends to metastasize early to the lymph nodes. It predominantly affects middle aged and elderly patients who have a history of alcohol and tobacco use. Patients may present with tonsillar swelling, sore throat, pain radiating to the ipsilateral ear, or a neck mass.;

Neoplastic status : Malignant;

Details

Origin ID

C8183;

UMLS CUI

C0280317;

Automatic exact mappings (from CISMeF team)
- Squamous cell carcinoma of tonsil [ICD-11 Subcategory]
Currated CISMeF NLP mapping
- Squamous cell carcinoma of tonsil [MedDRA LLT]
- tonsil squamous cell carcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Lip and Oral Cavity [NCIt concept]
- Neck [NCIt concept]
- Oral Cavity [NCIt concept]
- Oropharynx [NCIt concept]
- Pharynx [NCIt concept]
- Tonsil [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Squamous cell carcinoma of tonsil [MedDRA LLT]
- tonsil squamous cell carcinoma [DO Concept]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Squamous Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Squamous Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Oropharynx Epithelium [NCIt concept]
- Tonsillar Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Oropharynx [NCIt concept]
- Pharynx [NCIt concept]
- Throat [NCIt concept]
- Tonsil [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_molecular_abnormality
- EGFR Protein Overexpression [NCIt concept]

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