Preferred Label : Roxithromycin;
NCIt synonyms : Roxitromycine; 9-(2',5'-Dioxahexyloxyimino)erythromycin; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-d-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one;
NCIt related terms : (9E)-Erythromycin, 9-[O-[(2-methoxyethoxy)methyl]oxime];
NCIt definition : A semi-synthetic derivative of the macrolide antibiotic erythromycin that includes
an N-oxime side chain on the lactone ring, with antibacterial and anti-malarial activities.
Roxithromycin binds to the subunit 50S of the bacterial ribosome, which inhibits bacterial
protein synthesis and leads to inhibition of bacterial cell growth and replication.;
UNII : 21KOF230FA;
InChIKey : RXZBMPWDPOLZGW-XMRMVWPWSA-N;
CAS number : 80214-83-1;
Drug name : Rulide;
Molecule name : RU 28965; RU 965;
Chemical formula : C41H76N2O15;
ChEBI ID : CHEBI:48935;
Codes from synonyms : 50351;
Origin ID : C818;
UMLS CUI : C0035891;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
