Almurtide - CISMeF

Preferred Label : Almurtide;

NCIt synonyms : norMDP; N-Acetyl-nor-muramyl-L-alanyl-D-isoglutamine; nor-MDP; 2-Acetamido-3-O-((((1S)-1-(((1R)-1-carbamoyl-3- carboxypropyl)carbamoyl)ethyl)carbamoyl)methyl)-2-deoxy-D- glucopyranose;

NCIt definition : A synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP, almurtide activates both monocytes and macrophages. This results in the secretion of cytokines and induces the recruitment and activation of other immune cells, which may result in indirect tumoricidal or cytostatic effects.;

UNII : 1DCO35D4OR;

InChIKey : NWMHDZMRVUOQGL-CZEIJOLGSA-N;

CAS number : 61136-12-7;

Molecule name : Cgp-11637;

Chemical formula : C18H30N4O11;

Details

Origin ID

C81667;

UMLS CUI

C0130664;

Automatic exact mappings (from CISMeF team)
- reference standards [MeSH Descriptor]
Currated CISMeF NLP mapping
- N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine [MeSH concept]
- N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine [MeSH Supplementary Concept]
- N-acetyl-nor-muramyl-L-alanyl-D-isoglutamine [MeSH concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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