NCIt synonyms : Recombinant Human Deoxyribonuclease I;
NCIt definition : A recombinant human deoxyribonuclease I (rhDNAse) with selective DNA cleaving activity.
Upon intrapleural administration, dornase alfa catalyzes the degradation of extracellular
DNA in airway secretions, which can reduce their viscosity. Thus, dornase alfa may
both promote the clearing of airway mucus and improve pulmonary function.;