Pyridoxal Phosphate

Preferred Label : Pyridoxal Phosphate;

NCIt definition : The active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.;

UNII : 5V5IOJ8338;

InChIKey : CEEQUQSGVRRXQI-UHFFFAOYSA-N;

CAS number : 41468-25-1;

Chemical formula : C8H10NO6P.H2O;

Details

Origin ID

C81627;

UMLS CUI

C0034266;

Currated CISMeF NLP mapping
- Pyridoxal phosphate [ICD-11 Extension code]
- Pyridoxal phosphate [ICHI extension code]
- Pyridoxal phosphate [LOINC component]
- Pyridoxal phosphate (product) [Inactive SNOMED CT concept]
- Pyridoxal phosphate (substance) [SNOMED CT concept]
- pyridoxal 5'-(dihydrogen phosphate) [Substance BNPC]
- pyridoxal phosphate [MeSH Descriptor]
- pyridoxal phosphate [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
- Vitamin [UMLS semantic type]
UMLS correspondences (same concept)
- Pyridoxal phosphate [ICD-11 Extension code]
- Pyridoxal phosphate [LOINC component]
- Pyridoxal phosphate (product) [Inactive SNOMED CT concept]
- Pyridoxal phosphate (substance) [SNOMED CT concept]
- pyridoxal 5'-(dihydrogen phosphate) [Substance BNPC]
- pyridoxal phosphate [ATC Code]
- pyridoxal phosphate [MeSH Descriptor]
- pyridoxal phosphate [MeSH concept]
Validated automatic mappings to BTNT
- pyridoxal phosphate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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