Pleconaril - CISMeF

Preferred Label : Pleconaril;

NCIt synonyms : Picovir; 3-[3,5-Dimethyl-4-[3-(3-Methyl-5-Isoxazolyl)Propoxy]Phenyl]-5-(Trifluoromethyl)-1,2,4-Oxadiazole;

NCIt definition : A small-molecule inhibitor with activity against viruses in the picornaviridae family, including enterovirus and rhinovirus. Pleconaril binds to a hydrophobic pocket in the major capsid protein and prevents uncoating of the viral RNA genome. In enteroviruses it also prevents the virus from attaching itself to the host cell.;

UNII : 9H4570Q89D;

InChIKey : KQOXLKOJHVFTRN-UHFFFAOYSA-N;

CAS number : 153168-05-9;

Molecule name : Win-63843; VP-63843;

Chemical formula : C18H18F3N3O3;

Details

Origin ID

C81604;

UMLS CUI

C0759032;

Automatic exact mappings (from CISMeF team)
- 3-(3,5-dimethyl-4-(3-(3-methyl-5-isoxazolyl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole [MeSH concept]
- Pleconaril [ICD-11 Extension code]
- WIN 63843 [MeSH Supplementary Concept]
- picovir [MeSH concept]
Currated CISMeF NLP mapping
- pleconaril [MeSH concept]
- pleconaril [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- pleconaril [ATC Code]
- pleconaril [MeSH concept]
- pleconaril [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- pleconaril [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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