Preferred Label : Nortopixantrone;
NCIt definition : A 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone intercalates
into DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase
II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis.
Nortopixantrone is less cardiotoxicity than anthracyclines.;
UNII : PH2639TAB4;
InChIKey : PMGQHDIXCJMHRO-UHFFFAOYSA-N;
CAS number : 156090-17-4;
Chemical formula : C20H24N6O2;
Origin ID : C81423;
UMLS CUI : C2825625;
Semantic type(s)
- concept_is_in_subset
