" /> Eptacog Alfa - CISMeF





Preferred Label : Eptacog Alfa;

NCIt synonyms : Recombinant Factor VIIa; Recombinant Coagulation Factor VIIa; Coagulation Factor VIIa Recombinant Human; Recombinant FVIIa; rFVIIa; Coagulation Factor VIIa Recombinant;

NCIt related terms : Factor VIIa recombinant;

NCIt definition : A recombinant form of the vitamin K-dependent glycoprotein and coagulation factor VIIa (FVIIa), that can be used for the treatment of bleeding episodes and perioperative management in patients with hemophilia, congenital Factor VII (FVII) deficiency, and Glanzmann's thrombasthenia. Upon intravenous administration, eptacog alfa temporarily replaces missing endogenous FVIIa. When complexed with tissue factor (TF), FVIIa activates coagulation Factor X (FX) to Factor Xa (FXa), as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin. This converts fibrinogen to fibrin and leads to the formation of a hemostatic plug, thereby inducing local hemostasis and prevents bleeding.;

UNII : AC71R787OV;

CAS number : 102786-61-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 102786-61-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : NovoSeven RT; Novoseven;

Codes from synonyms : 209;

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25/05/2024


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