Preferred Label : Dopa, DL-;
NCIt synonyms : Dihydroxyphenylalanine,( -)-3-(3,4-Dihydroxyphenyl)alanine,DL-3,4-Dopa,( -)-Dopa; Dopa DL;
NCIt related terms : Dopamine;
NCIt definition : The racemic mixture of the precursor of dopamine L-DOPA (levodopa) and D-DOPA, with
antiparkinsonian properties. L-DOPA is converted to dopamine by DOPA decarboxylase
and can cross the blood-brain barrier (BBB). When in the brain, levodopa is decarboxylated
to dopamine and stimulates the dopaminergic receptors, thereby compensating for the
depleted supply of endogenous dopamine seen in Parkinson's disease.;
Alternative definition : ACC/AHA: Dopamine is a sympathomimetic drug that increases blood pressure and enhances
ventricular contractility.;
UNII : QI9C343R60;
InChIKey : WTDRDQBEARUVNC-UHFFFAOYSA-N;
CAS number : 63-84-3;
Chemical formula : C9H11NO4;
ChEBI ID : CHEBI:49168;
Origin ID : C81078;
UMLS CUI : C2825443;
Automatic exact mappings (from CISMeF team)
- Semantic type(s)
- concept_is_in_subset
