NCIt synonyms : Dysgerminoma of Ovary; Dysgerminoma of the Ovary; Germ Cell Dysgerminoma of Ovary; Germ Cell Dysgerminoma of the Ovary; Ovarian Germ Cell Dysgerminoma;
NCIt related terms : DYSGERMINOMA, MALIGNANT; Dysgerminoma;
NCIt definition : A malignant germ cell tumor arising from the ovary. Morphologically, it is identical
to seminoma and consists of a monotonous population of germ cells with abundant pale
cytoplasm and uniform nuclei. The stroma invariably contains chronic inflammatory
cells, mostly T-lymphocytes. It responds to chemotherapy or radiotherapy and the prognosis
relates to the tumor stage.;
Alternative definition : NICHD: A seminomatous germ cell tumor originating in the ovary.; CDISC: A malignant germ cell neoplasm characterized by the presence of a monotonous
primitive germ cell population, primarily in the ovary.; NCI-GLOSS: A type of tumor that begins in the type of cells that give rise to egg
cells and is most often found in the ovaries. Dysgerminomas may also occur in other
places in the body, including the central nervous system. They are the most common
type of ovarian germ cell tumor and can spread to other parts of the body. They are
most common in females who are younger than 20 years old.;