Preferred Label : Gadofosveset Trisodium Anhydrous;
NCIt definition : The anhydrous form of gadofosveset, an injectable, intravascular, amphiphilic gadolinium-based
contrast agent (GBCA) used with magnetic resonance angiography (MRA) imaging. Gadofosveset
is a stable gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) chelate derivative
with a diphenylcyclohexylphosphate group. Upon injection, gadofosveset binds reversibly
to endogenous serum albumin which increases its intravascular retention time compared
to non-protein binding contrast agents. The serum albumin binding also increases T1-relaxivity
of gadofosveset. This produces an increase in signal intensity of blood, thereby enhancing
the visualization of blood vessels upon MRA and may aid in the diagnosis of certain
blood vessels and heart disorders.;
UNII : 9430ZR8ZAN;
InChIKey : XGOSYNSWSRUASG-SSMZTGFVSA-H;
CAS number : 193901-90-5;
Chemical formula : C33H38N3O14P.Gd.3Na;
Origin ID : C81058;
UMLS CUI : C2825433;
Semantic type(s)
- concept_is_in_subset
