Falnidamol - CISMeF

Preferred Label : Falnidamol;

NCIt synonyms : EGFR Inhibitor BIBX 1382;

NCIt related terms : BIBX 1382;

NCIt definition : A pyrimido-pyrimidine with antitumor activity. BIBX 1382 inhibits the intracellular tyrosine kinase domain of the Epidermal Growth Factor Receptor (EGFR) thus specifically reversing the aberrant enzymatic activity from overexpressed and constitutively activated EGFR, and subsequently inhibiting cell proliferation and inducing cell differentiation.;

Alternative definition : NCI-GLOSS: A drug that may inhibit tumor cells from multiplying. It is being studied for its ability to treat cancer.;

UNII : 0MU316797D;

InChIKey : FTFRZXFNZVCRSK-UHFFFAOYSA-N;

CAS number : 196612-93-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 196612-93-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BIBX-1382;

Chemical formula : C18H19ClFN7;

Codes from synonyms : CDR0000046741;

Details

Origin ID

C80868;

UMLS CUI

C2825367;

Automatic exact mappings (from CISMeF team)
- BIBX 1382BS [MeSH concept]
- BIBX 1382BS [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Epidermal Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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