" /> Lapine T-Lymphocyte Immune Globulin - CISMeF





Preferred Label : Lapine T-Lymphocyte Immune Globulin;

NCIt synonyms : Antithymocyte Globulin Rabbit; Anti-Thymocyte Globulin Rabbit; Rabbit Anti-Thymocyte Globulin; Rabbit ATG; Rabbit Antithymocyte Globulin; Antithymocyte Globulin; Rabbit Anti-Human Thymocyte Globulin (RATG);

NCIt related terms : Antithymocyte globulin rabbit ATG;

NCIt definition : A preparation of purified, pasteurized, gamma globulin obtained by the immunization of rabbits with human thymocytes, with T-cell depleting and immunosuppressive activities. Upon administration, rabbit anti-thymocyte globulin (rATG) specifically recognizes, modulates and destroys T-lymphocytes. Although the exact mechanism of action by which rATG causes immunosuppression is not completely understood, it is likely caused by a combination of T-lymphocyte depletion and reduction in T-cell activation and their cytotoxic activities. Administering ATG with chemotherapy prior to stem cell transplantation may reduce the risk of graft-versus-host disease (GvHD).;

UNII : D7RD81HE4W;

CAS number : 308067-60-9;

Drug name : Thymoglobulin; Grafalon; Imtix;

NCI Metathesaurus CUI : CL554393;

Codes from synonyms : 37;

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08/05/2025


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