Human Immunoglobulin G

Preferred Label : Human Immunoglobulin G;

NCIt synonyms : Human IgG;

NCIt definition : A sterile preparation of purified immunoglobulin G (IgG) derived from large pools of human plasma. Upon administration, octagam provides passive immunization by increasing the recipient's serum levels of circulating antibodies. IgG antibodies have multiple functions, including binding to and neutralizing bacterial toxins; opsonization of pathogens; activation of complement; and suppression of pathogenic cytokines and phagocytes through binding to CD5, interleukin-1a (IL-1a), interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and T-cell receptors.;

UNII : 66Y330CJHS;

CAS number : 308067-58-5;

Drug name : Octagam; Hizentra; Flebogamma DIF; Privigen; Gamunex-C; Gammagard;

Details

Origin ID

C80829;

UMLS CUI

C2702333;

Automatic exact mappings (from CISMeF team)
- Product containing human immunoglobulin G (medicinal product) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Human immunoglobulin G (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Human immunoglobulin G (substance) [SNOMED CT concept]
- Product containing human immunoglobulin G (medicinal product) [SNOMED CT concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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