COX-2 Inhibitor

Preferred Label : COX-2 Inhibitor;

NCIt synonyms : PTGS2 Inhibitor; Prostaglandin-Endoperoxide Synthase 2 Inhibitor; Cyclooxygenase II Inhibitor;

NCIt related terms : cyclooxygenase-2 inhibitor;

NCIt definition : A subgroup of non-steroidal anti-inflammatory drugs (NSAID) that specifically targets at cyclooxygenase 2, an enzyme involved in pain and inflammation.;

Alternative definition : NCI-GLOSS: A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. COX-2 inhibitors are being studied in the prevention of colon polyps, and as anticancer drugs.;

ChEBI ID : CHEBI:50629;

Codes from synonyms : CDR0000044819; CDR0000044820;

Details

Origin ID

C80509;

UMLS CUI

C1257954;

Automatic exact mappings (from CISMeF team)
- Prostaglandin-endoperoxide synthase isoform 2 inhibitor (disposition) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Product containing prostaglandin-endoperoxide synthase isoform 2 inhibitor (product) [SNOMED CT concept]
- Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance) [SNOMED CT concept]
- cyclooxygenase 2 inhibitors [MeSH Descriptor]
- cyclooxygenase 2 inhibitors [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing prostaglandin-endoperoxide synthase isoform 2 inhibitor (product) [SNOMED CT concept]
- Substance with prostaglandin-endoperoxide synthase isoform 2 inhibitor mechanism of action (substance) [SNOMED CT concept]
- coxibs [ATC Code]
- cyclooxygenase 2 inhibitors [MeSH Descriptor]
- cyclooxygenase 2 inhibitors [MeSH concept]

Keyword's position in hierarchy(ies) :

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