Preferred Label : Stage III Laryngeal Cancer AJCC v6 and v7;
NCIt synonyms : Stage III Laryngeal Cancer AJCC v7; Stage III Carcinoma of the Larynx; Stage III Laryngeal Carcinoma; Stage III Laryngeal Cancer AJCC v6; Stage III Larynx Carcinoma; Stage III Carcinoma of Larynx; Laryngeal Cancer, Stage III;
NCIt related terms : stage III laryngeal cancer; Stage III Laryngeal Throat Cancer;
NCIt definition : Stage III includes: (T3, N0, M0); (T1, N1, M0); (T2, N1, M0); (T3, N1, M0). T1: Supraglottis:
Tumor limited to one subsite of supraglottis with normal vocal cord mobility. Glottis:
Tumor limited to the vocal cord(s) (may involve anterior or posterior commissure)
with normal mobility. Subglottis: Tumor limited to the subglottis. T2: Supraglottis:
Tumor invades mucosa of more than one adjacent subsite of supraglottis or glottis
or region outside the supraglottis (e.g., mucosa of base of tongue, vallecula, medial
wall of pyriform sinus) without fixation of the larynx. Glottis: Tumor extends to
supraglottis and/or subglottis, and/or with impaired vocal cord mobility. Subglottis:
Tumor extends to vocal cord(s) with normal or impaired mobility. T3: Supraglottis:
Tumor limited to larynx with vocal cord fixation and/or invades any of the following:
postcricoid area, pre-epiglottic tissues, paraglottic space, and/or inner cortex of
thyroid cartilage. Glottis: Tumor limited to the larynx with vocal cord fixation and/or
invasion of paraglottic space, and/or inner cortex of the thyroid cartilage. Subglottis:
Tumor limited to larynx with vocal cord fixation. N0: No regional lymph node metastasis.
N1: Metastasis in a single ipsilateral lymph node, 3cm or less in greatest dimension.
M0: No distant metastasis. (AJCC 6th and 7th eds.);
Alternative definition : NCI-GLOSS: Stage III laryngeal cancer depends on whether cancer has spread from the
supraglottis, glottis, or subglottis. In stage III cancer of the supraglottis, (1)
cancer is in the larynx only and the vocal cords cannot move, and/or cancer is in
tissues next to the larynx; cancer may have spread to one lymph node on the same side
of the neck as the original tumor and the lymph node is 3 centimeters or smaller;
or (2) cancer is in one area of the supraglottis and in one lymph node on the same
side of the neck as the original tumor; the lymph node is 3 centimeters or smaller
and the vocal cords can move normally; or (3) cancer is in more than one area of the
supraglottis or surrounding tissues and in one lymph node on the same side of the
neck as the original tumor; the lymph node is 3 centimeters or smaller. In stage III
cancer of the glottis, (1) cancer is in the larynx only and the vocal cords cannot
move, and/or cancer is in tissues next to the larynx; cancer may have spread to one
lymph node on the same side of the neck as the original tumor and the lymph node is
3 centimeters or smaller; or (2) cancer is in one or both vocal cords and in one lymph
node on the same side of the neck as the original tumor; the lymph node is 3 centimeters
or smaller and the vocal cords can move normally; or (3) cancer has spread to the
supraglottis and/or the subglottis, and/or the vocal cords cannot move normally; cancer
has also spread to one lymph node on the same side of the neck as the original tumor
and the lymph node is 3 centimeters or smaller. In stage III cancer of the subglottis,
(1) cancer is in the larynx and the vocal cords cannot move; cancer may have spread
to one lymph node on the same side of the neck as the original tumor and the lymph
node is 3 centimeters or smaller; or (2) cancer is in the subglottis and in one lymph
node on the same side of the neck as the original tumor; the lymph node is 3 centimeters
or smaller; or (3) cancer has spread to one or both vocal cords, which may not move
normally; cancer has also spread to one lymph node on the same side of the neck as
the original tumor and the lymph node is 3 centimeters or smaller.;
Neoplastic status : Malignant;
Codes from synonyms : CDR0000045283;
Origin ID : C8043;
UMLS CUI : C4520750;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Disease excludes abnormal cell
- Has associated anatomic sites
- Semantic type(s)
- concept_is_in_subset
- disease_excludes_finding
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_is_stage
