Retinoic Acid Agent

Preferred Label : Retinoic Acid Agent;

NCIt synonyms : Retinoid; Retinoids; Retinoic Acids; Retinoic Acid and Derivatives;

NCIt definition : A group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities. A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization. (NCI04);

Alternative definition : NCI-GLOSS: A nutrient that the body needs in small amounts to function and stay healthy. Retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo. A form of retinoic acid made in the laboratory is put on the skin to treat conditions such as acne and is taken by mouth to treat acute promyelocytic leukemia (a fast-growing cancer in which there are too many immature blood-forming cells in the blood and bone marrow). Retinoic acid is being studied in the prevention and treatment of other types of cancer.;

ChEBI ID : CHEBI:26537;

Codes from synonyms : CDR0000045870;

Details

Origin ID

C804;

UMLS CUI

C0035339;

Currated CISMeF NLP mapping
- Product containing retinoid (product) [SNOMED CT concept]
- retinoids [IUPAC Term]
- retinoids [MeSH Descriptor]
- retinoids [MeSH concept]
See also inter- (CISMeF)
- Retinoid (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing retinoid (product) [SNOMED CT concept]
- Retinoid (substance) [SNOMED CT concept]
- retinoids [IUPAC Term]
- retinoids [MeSH Descriptor]
- retinoids [MeSH concept]
Validated automatic mappings to BTNT
- Retinoic acid [ICD-11 Extension code]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients