B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged

Preferred Label : B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); KMT2A Rearranged;

NCIt synonyms : B-Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); MLL Rearranged; B Lymphoblastic Leukemia/Lymphoma with t(v;11q23.3); MLL Rearranged; B Lymphoblastic Leukemi Lymphoma with t v 11q23 MLL Rearranged; B-Lymphoblastic Leukemia/Lymphoma with KMT2A Rearrangement; B Lymphoblastic Leukemia/Lymphoma with KMT2A Rearrangement; B Lymphoblastic Leukemia/Lymphoma with T(V;11Q23); MLL Rearranged;

NCIt definition : A precursor lymphoid neoplasm which is composed of B lymphoblasts and carries a translocation between the KMT2A gene at 11q23.3 and another gene partner resulting in the production of an KMT2A related fusion protein.;

Neoplastic status : Malignant;

ICD-O code : 9813/3;

Details

Origin ID

C80332;

UMLS CUI

C2698309;

Automatic exact mappings (from CISMeF team)
- B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged (morphologic abnormality) [SNOMED CT concept]
Currated CISMeF NLP mapping
- B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged (disorder) [SNOMED CT concept]
- B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) [ORDO Disease]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Mature B-Lymphocyte [NCIt concept]
- Myeloid Cell [NCIt concept]
Disease may have findings
- Hepatomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- t(v;11q23.3) [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged (disorder) [SNOMED CT concept]
- B lymphoblastic leukemia lymphoma with t(v;11q23); MLL rearranged (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Blasts of Mixed Phenotype Present [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphoblast [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphoblast [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Recurrent Genetic Abnormalities Present [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- KMT2A Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphoblast [NCIt concept]
- Lymphocyte [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- KMT2A Gene [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
pathogenesis_of_disease_involves_gene
- KMT2A Gene [NCIt concept]
- KMT2A wt Allele [NCIt concept]

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