Monoclonal B-Cell Lymphocytosis

Preferred Label : Monoclonal B-Cell Lymphocytosis;

NCIt synonyms : MBL;

NCIt definition : A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia. It precedes virtually all cases of chronic lymphocytic leukemia/small lymphocytic lymphoma.;

Alternative definition : NCI-GLOSS: A condition in which a higher-than-normal number of identical B cells are found in the blood. People with MBL may develop other B-cell diseases, such as chronic lymphocytic leukemia (CLL).;

Neoplastic status : Undetermined;

Codes from synonyms : CDR0000630931; CDR0000630932;

Details

Origin ID

C80310;

UMLS CUI

C2698259;

Automatic exact mappings (from CISMeF team)
- Immunodeficiency with MBL - [mannan-binding lectin] deficiency [ICD-11 More detail]
- Mannose-binding lectin 2 [OMIM gene]
- Mannose-binding protein [LOINC component]
- Monoclonal B-cell lymphocytosis (disorder) [SNOMED CT concept]
- Monoclonal B-cell lymphocytosis (morphologic abnormality) [SNOMED CT concept]
- mannose-binding lectin [MeSH Descriptor]
Currated CISMeF NLP mapping
- Monoclonal B-cell lymphocytosis [MedDRA Preferred Term]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Monoclonal B-cell lymphocytosis [MedDRA Preferred Term]
- Monoclonal B-cell lymphocytosis (disorder) [SNOMED CT concept]
- Monoclonal B-cell lymphocytosis (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Lymphocytosis [NCIt concept]
- Monoclonal Cellular Population Present [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

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