Gadoterate Meglumine

Preferred Label : Gadoterate Meglumine;

NCIt synonyms : Gd-DOTA;

NCIt definition : A gadolinium chelate paramagnetic contrast agent. When placed in a magnetic field, gadoterate meglumine produces a large magnetic moment and so a large local magnetic field, which can enhance the relaxation rate of nearby protons; as a result, the signal intensity of tissue images observed with magnetic resonance imaging (MRI) may be enhanced. Because this agent is preferentially taken up by normal functioning hepatocytes, normal hepatic tissue is enhanced with MRI while tumor tissue is unenhanced. In addition, because gadobenate dimeglumine is excreted in the bile, it may be used to visualize the biliary system using MRI.;

UNII : L0ND3981AG;

InChIKey : RYHQMKVRYNEBNJ-BMWGJIJESA-K;

CAS number : 92943-93-6;

Drug name : DOTAREM;

Chemical formula : C16H24N4O8.C7H17NO5.H.Gd;

Details

Origin ID

C80124;

UMLS CUI

C0118538;

Automatic exact mappings (from CISMeF team)
- Product containing gadoterate meglumine (medicinal product) [SNOMED CT concept]
- gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate [MeSH Supplementary Concept]
- gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate [MeSH concept]
CISMeF manual mappings
- Gadoterate meglumine (substance) [SNOMED CT concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Gadoterate meglumine (substance) [SNOMED CT concept]
- Product containing gadoterate meglumine (medicinal product) [SNOMED CT concept]
- gadoterate meglumine [Radlex concept]
- gadoterate meglumine [MeSH Supplementary Concept]
- gadoterate meglumine [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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