BTG1 wt Allele

Preferred Label : BTG1 wt Allele;

NCIt synonyms : B-Cell Translocation Protein 1 Gene; APRO2; BTG Anti-Proliferation Factor 1 wt Allele; B-Cell Translocation Gene 1, Anti-Proliferative Gene;

NCIt definition : Human BTG1 wild-type allele is located in the vicinity of 12q22 and is approximately 3 kb in length. This allele, which encodes protein BTG1, which plays a role in the modulation of cellular proliferation. Genetic variation may be associated with the relapse of acute lymphoblastic leukemia. The BTG1 gene and the MYC gene are involved in a chromosomal aberration, translocation t(8;12)(q24;q22), which may be associated with B-cell chronic lymphocytic leukemia.;

GenBank Accession Number : NM_001731;

PubMed : 19039135;

Details

Origin ID

C80103;

UMLS CUI

C2698303;

OMIM relation
- B-cell antiproliferation factor 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q22 [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cell Proliferation [NCIt concept]

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