Preferred Label : Cefprozil Anhydrous, (Z)-;
NCIt synonyms : Cefprozil Anhydrous, Z-Isomer; Cefprozil Anhydrous Z-Isomer;
NCIt definition : The anhydrous form of the Z-isomer of a semi-synthetic cephalosporin and a beta-lactam
antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding
to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane.
Binding results in the inhibition of the transpeptidase enzymes, thereby preventing
cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide
and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil
inhibits bacterial septum and cell wall synthesis formation.;
UNII : W5T767OA4G;
InChIKey : WDLWHQDACQUCJR-AGGBKSKLSA-N;
CAS number : 121412-77-9;
Chemical formula : C18H19N3O5S;
Origin ID : C80091;
UMLS CUI : C2699145;
Semantic type(s)
- concept_is_in_subset
