" /> Ioflubenzamide I-131 - CISMeF





Preferred Label : Ioflubenzamide I-131;

NCIt synonyms : Iodine I 131 MIP-1145; N-(2-(diethylamino)ethyl)-4-((4-fluorobenzoyl)amino)-5-((sup 131)I)iodo-2-methoxybenzamide; Ioflubenzamide (131I);

NCIt definition : An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic activity. The benzamide moiety of 131-I-MIP-1145 binds to melanin, selectively delivering a cyotoxic dose of gamma and beta radiation to melanin-expressing tumor cells. Melanin pigments, polymer derivatives of the amino acid tyrosine, are over-expressed in approximately 40% of melanomas.;

UNII : 65O1D58Z6V;

InChIKey : UPRRZQGAQRAODM-AWUWEVMDSA-N;

CAS number : 1214283-52-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1214283-52-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : MIP-1145;

Chemical formula : C21H25FIN3O3;

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15/05/2024


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