Preferred Label : Ioflubenzamide I-131;
NCIt synonyms : Iodine I 131 MIP-1145; N-(2-(diethylamino)ethyl)-4-((4-fluorobenzoyl)amino)-5-((sup 131)I)iodo-2-methoxybenzamide; Ioflubenzamide (131I);
NCIt definition : An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic
activity. The benzamide moiety of 131-I-MIP-1145 binds to melanin, selectively delivering
a cyotoxic dose of gamma and beta radiation to melanin-expressing tumor cells. Melanin
pigments, polymer derivatives of the amino acid tyrosine, are over-expressed in approximately
40% of melanomas.;
UNII : 65O1D58Z6V;
InChIKey : UPRRZQGAQRAODM-AWUWEVMDSA-N;
CAS number : 1214283-52-9;
Molecule name : MIP-1145;
Chemical formula : C21H25FIN3O3;
Origin ID : C80056;
UMLS CUI : C3272212;
Semantic type(s)
- concept_is_in_subset
